Joe Manganiello published his memoir Bloodlines on October 13, 2026, writing about a near-fatal autoimmune disease that went undiagnosed for nearly a decade and about the end of his marriage to Sofía Vergara. The book says Vergara authorized a 10-hour operation to remove his entire large intestine, that he lost 60 pounds in two weeks and later had reconstructive surgery, and that he turned to hydrocodone, fentanyl patches and marijuana while 13 years sober, once asking her to hide his gun. It also claims she refused to hug him and ridiculed his chihuahua Bubbles, and that his team believed Tom Cruise vetoed his Jack Reacher casting over Vergara. Vergara has not responded on the record.